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Jyutping tung3 sam1 zat6 sau2
Pinyin tòng xīn jí shǒu

Definitions (CC-CEDICT)
  1. bitter and hateful (idiom)
  2. to grieve and lament (over sth)
Definitions (粵典–words.hk)
  1. 形容詞
    痛心​、​怨恨​到極
    with deep hatred and resentment
    • 佢一日一日咁變壞,令到父母痛心疾首。
      佢一日一日咁变坏,令到父母痛心疾首。
      keoi5 jat1 jat6 jat1 jat6 gam2 bin3 waai6, ling6 dou3 fu6 mou5 tung3 sam1 zat6 sau2.
      His behaving worse and worse makes his parents deeply desperate.
Definitions (Wiktionary)
  1. phrase, idiomatic
    to be deeply sorrowful and intensely grieve for or abhor something
Definitions (Kaifangcidian)
  1. (沒有對應漢語詞彙)
Examples (粵典–words.hk)
  1. Cantonese
    佢一日一日咁变坏,令到父母痛心疾首。
    佢一日一日咁變壞,令到父母痛心疾首。
    keoi5 jat1 jat6 jat1 jat6 gam2 bin3 waai6, ling6 dou3 fu6 mou5 tung3 sam1 zat6 sau2.
    • His behaving worse and worse makes his parents deeply desperate.